Novel Research Models for Staphylococcus aureus Small Colony Variants (SCV) Development: Co-pathogenesis and Growth Rate
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چکیده
منابع مشابه
Genetic Complexity of Fusidic Acid-Resistant Small Colony Variants (SCV) in Staphylococcus aureus
FusE mutants are fusidic acid-resistant small colony variants (SCVs) of Staphylococcus aureus that can be selected with aminoglycosides. All FusE SCVs have mutations in rplF, encoding ribosomal protein L6. However, individual FusE mutants including some with the same mutation in rplF display auxotrophy for either hemin or menadione, suggesting that additional mutations are involved. Here we sho...
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Staphylococcus aureus remains a versatile and dangerous pathogen. Small-colony variants (SCVs) of S. aureus are a naturally occurring sub-population, first described nearly 100 years ago. These variants, of which there are different classes, grow slowly and have many atypical characteristics thought to be due to defective electron transport, and include minute colony forms. SCVs have been isola...
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variants (SCVs) !" sub-MIC triclosan (TLN) # $ %& ' ( !) TLN SCVs*"+,!" "+#. 2 $'(/0 %1, 4 $ . &' 2&34$56* SCVs (7,68!" %9: SCVs;. MIC*)< * 25+= ;',$ >DNase .? @ABCDEF/ G4H0IJKLM12 3NO * 4$ PQ R( 5S6TU7V:9!" =! TLN WDXYZ;R enoyl reductase enzyme (FabI) Ala95[ValU,\. Thr147[His A]^_(` /a68!" TLN SCVs. b 886c9:;,6U *? =;o@,!"A '...
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ژورنال
عنوان ژورنال: Frontiers in Microbiology
سال: 2020
ISSN: 1664-302X
DOI: 10.3389/fmicb.2020.00321